TESTOSTERONE 400 - 400 mg / 10mL
Each milliliter of the oily solution contains the following:
Form of the drug: Clear oil solution from slightly yellow to yellow colour with characteristic smell.
Pharmacological properties: Testosterone 400 consists of three Testosterone esters. The testosterone is the main sex hormone which is synthesized and secreted by the testis. It stimulates the growth and the development of the male reproductive organs and secondary sexual characteristics (prostate maturation, seminal vesicles, the penis and the scrotum) It stimulates the production of erythropoietin and red blood cells. The negative side is that it Suppresses spermatogenesis. Women- Inhibits gonadotrophin, Function of the pituitary gland, the functions of the ovarie. There is beneficial effect during the Climacteric complaints.
Pharmacokinetic properties: The esters in Testosterone 400 have different absorption rates and excretion. So there is excellent effect (4 weeks) after the injection. The effect of Testosterone phenylpropionate and Testosterone propionate starts 24 hours after the injection and lasts up to 2 weeks. The effect of Testosterone decanoate starts later. Biotransformation is in the liver. (6% is in the Stools).
Dosage and How to Take It: This medicine is given intramuscularly as directed by your pharmacist. It should not be administered intravenously. Intramuscular injections should be given deep in the gluteal muscle. The dose depends from the patients, the disease state, sex, Clinical effectiveness. Male infertility: 2 ml once every two weeks (Resolving a painful erection). Women with breast cancer : 1-2 ml every 1- 2 weeks (Prolonged treatment). IT SHOULD NOT BE GIVEN INTRAVENOUSLY!
Side effects: Priapizym, adults - prostate cancer, Hypertrophy, Frequent erection, Penis enlargement, Little ejaculation, Problems with the prostate gland, Reduction of spermogenesis, Accelerates sexual maturation Women: virilizing symptoms, change in the menstrual period, inhibition of ovarian function Hypercalcemia It is possible to has pain, itching and redness at the injection site. Patients should be instructed to report any of the following: nausea, vomiting, changes in skin color, ankle swelling, too frequent or persistent erections of the penis.
Contraindications: Oversensitivity to the steroids, prostate cancer, breast cancer, atherosclerosis, kidney failure, pregnancy, Breastfeeding, Nephrotic syndrome, Cardiac and coronary insufficiency.
Overdose: Overdose may develop Priapism. In this case we should stop the treatment and then start with lower dose.
Preventive measures: When there are androgen-dependent unwanted reactions we should stop the treatment with testosterone and then start with lower dose. Patients with latent or apparent heart failure, renal dysfunction, high blood pressure, Epilepsy or migraine are under constant surveillance. Patients with breast cancer, Lung cancer with bone metastases – check the level of calcium in the blood and urine Boys in puberty – use the Androgens with caution.
Storage: It should be stored in a dry place away from heat and humidity. 15° to 25° C (59° to 77° F) Keep Testosterone 400 out of the reach of children and away from pets. Do not refrigerate or freeze; Store in the original package in order to protect from light Do not throw away any medicines via wastewater or household waste. Ask your Pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
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